modafinil will reduce the extent or effect of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Inhibition of platelet aggregation by clopidogrel is entirely resulting from an Energetic metabolite. Clopidogrel is metabolized to this Energetic metabolite partly by CYP2C19. .
saquinavir will improve the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
ribociclib will improve the degree or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Stay away from coadministration of ganaxolone with average or powerful CYP3A4 inducers. If coadministration unavoidable, take into consideration increasing ganaxolone dose; having said that, will not exceed greatest day by day dose for excess weight.
Prescription drugs that have constraints other than prior authorization, quantity limits, and action therapy connected to Every prescription.
Metabolism: Modafinil undergoes hepatic metabolism by using several pathways, like CYP3A4. 80% of the dose is recovered from the urine in the shape of metabolites.
Persistent Sleepiness: Keep track of people often for your diploma of sleepiness and, if appropriate, endorse clients in order to avoid engaging or driving in almost every other probably dangerous exercise.
nelfinavir will improve the stage or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 check here metabolism. Use Caution/Watch.
Any dose that is 50 mg or fewer is considered a microdose— that means which the dose is beneath the therapeutic threshold.
The usage of Program I medication in Japan is mostly prohibited, besides underneath certain conditions, for instance for medical reasons. It could possibly only be prescribed by a health care provider. It can not be imported or exported without having a permit.
For change get the job done slumber ailment: Adults and youngsters 17 several years of age and more mature—two hundred milligrams (mg) a person hour before you begin Operating. Adolescents and youngsters young than seventeen several years of age—Use and dose have to be determined by your medical doctor. Skipped Dose For those who miss out on a dose of the medication, skip the skipped dose and return to your common dosing agenda. Will not double doses.
modafinil will enhance the level or impact of flibanserin by impacting hepatic enzyme CYP2C19 metabolism.
From postmarketing experience, there have already been experiences of fatal overdoses involving modafinil on your own or together with other prescription drugs. Signs and symptoms most often accompanying PROVIGIL